University of Cape Town leads in plant-based HPV vaccine research

first_img20 October 2014The University of Cape Town’s Biopharming Research Unit (BRU) group developed the “first proof of efficacy of a plant-produced papillomavirus vaccine’. The unit’s breakthrough now sees it collaborating with Medicago, a Canadian biopharmaceutical company, to produce a plant based-HPV vaccine.The human papilloma virus is indicated in causing a number of cancers, the most well-known of which is cervical cancer. This type of cancer is the most common cause of cancer-related deaths among women in South Africa.According to a paper by Amy Kirkpatrick Brown, MD, MPH and Richard G Moore, MD FACOG at the Programme on Women’s Oncology at Brown University in the US, “ease of administration and production are the obvious strengths of plant-based vaccines’. Considering that the HPV vaccine is expensive for the majority of developing countries, introducing rapid, cost-effective production to increase the amount of the vaccine available would drive down costs.Biopharming Research Unit director Professor Ed Rybicki said plants make particularly effective factories for biological products: they are easy and inexpensive to grow and maintain, and can produce complex biological products quickly and reliably.According to a statement from the University of Cape Town, Medicago is providing funding and some materials for the research, while the BRU will provide the expertise to develop and produce the virus-like particles that will be used as vaccines against HPV.Marc-Andre D’Aoust, vice president of research and innovation at Medicago said: “This collaboration has the potential to bring forth novel vaccine solutions against human papillomaviruses that provide improved protection from the wide variety of circulating virus strains.”In the statement from UCT, Rybicki said the BRU has been perfecting their process for years and was the first group worldwide to produce significant amounts of HPV protein in plants.According to the UCT statement, the group has around 17 years’ experience in producing proteins and virus-like particles in plants. Aside from HPV, the group has also worked on human immunodeficiency virus (HIV), avian and human influenza, as well as animal viruses such as bluetongue virus, and beak and feather disease virus.The BRU has the largest molecular biotechnology portfolio in South Africa.South Africa’s HPV immunisation programmeSouth Africa is the first African country to introduce an HPV immunisation programme. In 2013 health minister Aaron Motsoaledi announced that the provision of the vaccines for girls aged 9 to 10 in the “poorest 80% of schools starting in February 2104′.SAinfo reporterlast_img read more

Anil Agarwal to exit from Anglo American to divest 193 stake

first_imgNew Delhi: Two years after becoming the biggest shareholder of the firm that owns De Beers diamonds, metals tycoon Anil Agarwal announced an exit from Anglo American by divesting his near 20 per cent stake. He had in March 2017, began buying into Anglo American through a JP Morgan mandatory convertible bond and by the time he bought a second tranche in September 2017, his stake in the mining group totalled to 19.3 per cent. The bonds were to mature next year but Agarwal decided to exercise a call option and take profits on his investment. Also Read – Thermal coal import may surpass 200 MT this fiscalAgarwal is said to have made about $500 million before costs from the deal. “At the time of Volcan’s (Agarwal’s family trust) initial investment, I explained that this was an attractive financial investment in a great company with excellent assets and a strong board and management team,” he said in a statement. “This has turned out to be the case, with our target returns achieved even sooner than expected. The share price of Anglo American has close to doubled since Volcan invested, delivering attractive gains to all investors.” Also Read – Food grain output seen at 140.57 mt in current fiscal on monsoon boostIn a separate statement, Vedanta Ltd said its overseas subsidiary, Cairn India Holdings Ltd (CIHL) will exit its investments in Anglo American Plc. In December 2018, CIHL purchased an economic interest through a structured investment in equity shares of Anglo-American Plc, from Volcan Investments – Agarwal’s family trust, for a total consideration of Rs 3,812 crore. “CIHL and Volcan Investments Ltd have agreed to unwind entirely the structured investment entered between them in December 2018, ahead of the originally envisaged schedule,” Vedanta said in a statement. “With this, Volcan will exercise the early exchange option available to it on July 26, 2019, and consequent to this the full exchange of its two issues of mandatory exchangeable bonds secured by shares in Anglo American plc will settle on August 12, 2019.” This structure was to mature in parts in April 2020 and October 2020 but Cairn is exiting the same ahead of the originally envisaged schedule. “The share price of Anglo American has close to doubled, since Volcan invested, delivering attractive gains to all investors,” the statement said. The investment by CIHL, which was entered into as part of its cash management activities, has delivered a net gain of over $100 million in the 8 month period it was held, it added. Cash proceeds from the settlement of the transaction will be paid to CIHL on August 13, 2019. Chief executive Srinivasan Venkatakrishnan said: “We are pleased this structured investment has achieved a superior return for CIHL, as we expected when it was entered into. Our strategy continues to be to focus on our existing businesses, where we believe that there are significant opportunities to unlock their full potential.” “The unwinding reflects our disciplined approach to treasury management and capital allocation together with our commitment at all times to act in the interests of all shareholders,” he said. Following the redemption of the structured instrument, completed with due Board approvals, CIHL will have no further economic exposure to Anglo American plc shares.last_img read more

GB Hospital Returning to Normal Minister Applauds Staffs Effective Emergency Response

first_imgFacebook Twitter Google+LinkedInPinterestWhatsApp Recommended for you The Luxury of Grace Bay in Down Town Provo ALERT # 2 ON POTENTIAL TROPICAL CYCLONE NINE ISSUED BY THE BAHAMAS DEPARTMENT OF METEOROLOGY THURSDAY 12TH SEPTEMBER, 2019 AT 9 PM EDT Related Items:#magneticmedianews Facebook Twitter Google+LinkedInPinterestWhatsAppBahamas, July 24, 2017 – Grand Bahama – Cleanup at the Rand Memorial Hospital is underway since the kitchen fire and evacuation on Friday, July 21. And 20 of the 48 patients evacuated to Christ the King, have been returned, said Minister of Health, Dr. the Hon. Duane Sands, during a press briefing on Sunday afternoon, July 23, 2017.Minister Sands praised Acting Hospital Administrator, Mrs. Sandra Mortimer-Russell, along with the Executive Management Committee and staff of the Rand Memorial Hospital for “stepping up to the plate on Friday past, thereby averting what could have been a far more serious event. I do not say that to minimize the incident, but to highlight the fact that I am indeed proud and grateful for a job well done.”The fire reportedly started at 2:30 p.m. on Friday in the kitchen of the Rand Memorial Hospital. Staff and patients were evacuated and taken to the Foster B. Pestaina Centre of Christ the King Anglican Church, and the more critical patients taken to the Sunrise Medical Centre.“We can now confirm the initial report that most of the damage was limited to the kitchen area. Other areas impacted by smoke include: Medical, Surgical, Obstetric and Pediatric Wards, Cafeteria and the Intensive Care Unit (ICU). Clean up of those areas will be completed today. Plans are now at an advanced stage to restore the kitchen so as to meet the onsite dietary needs of our patients and staff. In the interim, discussions are underway to determine the comparative cost of outsourcing the services of the kitchen given that a new state of the art kitchen and cafeteria is under construction.”Reporting on the other 28 patients evacuated to Christ the King on Friday, Minister Sands said they have been discharged by their attending physicians and the usual follow up by the community nursing teams will take place.As of 8:00 a.m. on Sunday, eight patients were still at Sunrise Medical Centre and are being cared for by the staff of the Rand’s medical, nursing and support teams. The two acutely ill patients scheduled to be transported to Nassau on Friday, were done so that evening at 7:00 p.m.No patients were injured during the fire or evacuation exercise; however, three staff members were treated for smoke inhalation. Two were treated and immediately released, while one was admitted to Sunrise Medical Centre. He has been since released and scheduled to return to work today.The public is reminded that the Accident/Emergency and Urgent Care Unit of the Rand Memorial Hospital is open 24 hours for emergencies only. The Outpatients Specialty Clinic at Pearce Plaza on Coral Road is currently open 24 hours for non-urgent cases. Eight Mile Rock Clinic is also open 24 hours and the pharmacy services at these locations are also open 24 hours to fill prescriptions.A Command Centre has been established to provide information to the public, and the numbers there are: 351-8056 or 7, or 350-6761-3.“My Ministry and indeed the Public Hospitals Authority remain grateful to the organizations that partnered with us to accommodate our clients. It was a wonderful reminder of what we can do together.”The Minister ended the press briefing with good news. The patient, who had been evacuated while in labor on Friday, gave birth to a healthy baby boy at Sunrise Medical Centre.#magneticmedianews Electricity Cost of Service Study among the big agenda items at September 11 Cabinet meetinglast_img read more

Strong Santa Ana winds prompt red flag warning for San Diego County

first_img SAN DIEGO (KUSI) – Strong and gusty Santa Ana winds, low humidity and warm temperatures prompted the National Weather Service to issue a red flag fire warning Friday denoting a strong risk of wildfire in San Diego County.Along with low humidity levels, the strong Santa Ana winds blowing northeast are to blame for the fire danger, with winds of 15 to 25 mph in the forecast and gusts near 45 mph possible in the county mountains, according to the Santa Ana Wildfire Threat Index. Humidity was expected to drop to 15-20 percent Friday.The red flag warning went into effect at 3 Friday morning and will last until 10 p.m. Friday evening for the county mountains and valleys.Vegetation will be dry enough to result in rapid spread of flames should ignition occur, according to the wildfire threat index.San Diego County residents were urged to avoid outdoor burning during the warning.Warm seasonal temperatures were also expected to add to the potential fire danger. High temperatures Friday will be 85 to 87 degrees near the coast and inland, 86 to 91 degrees in the western valleys, 79 to 84 in the foothills, 69 to 76 in the mountains and around 87 in the deserts, NWS forecasters said.According to Cal Fire San Diego Unit Chief Tony Mecham, residents should take measures to safeguard themselves and their homes, including clearing flammable vegetation to create roughly 100 feet of “defensible space” around residences; developing an emergency evacuation plan; and planning in advance which important documents, heirlooms, photos and medications to quickly gather prior to any evacuation.County officials also recommend that residents register their mobile phones on the county’s emergency-alert system, AlertSanDiego, and download the free SD Emergency App. Residents can learn more about fire safety and preparedness online at ReadySanDiego.org.“The humidity will recover tonight and not be as low on Saturday with gusty winds diminishing Saturday afternoon,” NWS forecasters said. October 19, 2018 KUSI Newsroom KUSI Newsroom, Posted: October 19, 2018 Strong Santa Ana winds prompt red flag warning for San Diego County Categories: Local San Diego News, Weather FacebookTwitterlast_img read more

HP offers tour of your digital future

first_img(PhysOrg.com) — Never mind that HP Corporate keeps breaking off rudders. Never mind nobody even takes HP’s ability to stay open in the future for granted any more. And, please, never mind that HP, pre-Meg, was to turn its back on hardware and concentrate on software, a decision that is now up in the air. Just ignore the uncertainty and enjoy the view of four device concepts. HP’s creatives are still barreling ahead in their own rowboats while everyone outside HP clucks at the mothership. The HP Curve from top to bottom is an “immersive” design that combines a flat interactive surface with a vertical transparent display and on the side a back to the future inkwell concept of a stylus perched and ready for writing. It is a large tabletop size device that looks far more like a Milan-inspired furniture item, which may explain the HP promotional message of the HP Curve being “designed to be built into a room.” © 2011 PhysOrg.com Explore further Citation: HP offers tour of your digital future (2011, September 29) retrieved 18 August 2019 from https://phys.org/news/2011-09-hp-digital-future.html This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. The HP Flex, with a see-through screen, is a flexible laptop that the actors in the movie use to control the robots during battle. The Original Noisy Boy Controller was imagined as a dual display flexible laptop that can be used even when closed. Working with the DreamWorks team to create the right look for the concept, the final design turned out to be a clam shell-shaped controller, stylized to match the robot Noisy Boy. HP renames EDS, now HP Enterprise Services A team at HP was asked to help DreamWorks conceptualize technology of the future. The upcoming movie Real Steel with Hugh Jackman inspired HP’s winning ideas; as a not so sneaky preview, HP is showcasing four of its Real Steel technology concepts of what computing will look like in the future. The samples remind us that computing can always find room for beautiful forms for computing.An HP ThruScreen is HP’s way of allowing a user to manipulate and interact with real and virtual objects behind a transparent adjustable screen. You can rotate the screen to place objects behind the screen or below the screen The HP Volume Jet is a 3-D printer crafted as a future iteration of the HP DesignJet 3D. The DreamWorks team and the HP creatives built a Volume Jet prototype but it did not make the final cut. It’s a large desktop surface when it is flat, a notebook when open, and a tablet when loaded, with “ergonomic” grip power.HP has enjoyed a long relationship with DreamWorks. HP and DreamWorks Animation formed a technology partnership in 2001. The partnership between DreamWorks and HP has extended both to the studio’s infrastructure and business divisions.last_img read more